The May update to the AHFS Drug Information/Essentials database was published today. Highlights from this month’s update include:

New AHFS/Essentials Monographs

• Ganciclovir (Zirgan^®)
  • The ophthalmic gel is indicated for the topical treatment of acute herpetic keratitis in patients with dendritic ulcers

FDA MedWatch Alerts

• Metformin
  • Revised warnings in reduced kidney function
• Fluconazole
  • FDA is evaluating the results of a Danish study that concluded there is a possible increased risk of miscarriage with the use of oral fluconazole for yeast infections
• Aripiprazole
  • Warning regarding compulsive or uncontrollable urges to gamble, binge eat, shop, and have sex have been reported
• Ticagrelor and Vortioxetine
  • Brand name change for vortioxetine (Brintellix) due to name confusion with ticagrelor (Brilinta)